Exploring the Antioxidant and Anti-Inflammatory Potential of Wilckia maritima: In Vitro and In Silico Investigations

This research aimed to assess the anti-inflammatory and antioxidant potential of methanol extract Wilckia maritima, a plant belonging family Brassicaceae, which is enriched with natural antioxidants. Qualitative phytochemical studies showed presence numerous compounds including glycosides, phenols, triterpenoids, GC-MS revealed 35 bioactive components, n-hexadecanoic acid (26.96%), 9,12,15 octadecatrienoic (cis) (25.52%), 3,5 di-hydroxy-6-methyl 2,3-di-hydro-4-pyran 4-one (14.35%), 3-tertiary butyl-4-hydroxy-anisol (11.68%) as major are thought be responsible for potentials W. maritima., flavonoids, steroids, tannins, saponins. The was determined by performing various assays, DPPH free radical scavenging, ferrous reducing, hydrogen peroxide significant percentage inhibition (83.55 ± 0.89, 79.40 1.17, 81.26 0.36%, respectively) compared ascorbic (standard). also exhibited activity 65.66 0.42% standard ibuprofen, 73.20 0.21% inhibition. In vivo analysis further confirmed this extract, showing 75.55 0.11% reduction in edema at 300 mg/kg diclofenac sodium 70.27 0.012%. Moreover, silico investigations that phytocompounds maritima excellent characteristics, could provide novel biological molecules target receptors. Overall, our findings suggest can utilized resource antioxidants potential, promising therapeutic effect relieving ailments related inflammatory response.